Usually, you get diseases due to multiple factors, like genetics, lifestyle, and surroundings. In such cases, the genetic risk is not calculated based on one variant but on numerous common variants spread across the genome. This collective risk is termed as a polygenic risk. The physical endurance screening utilizes a Polygenic Risk Score (PRS) model which estimates an individual’s risk for a certain trait or condition. It sums up all known common variants to calculate an overall genetic risk for that specific condition. After calculating the polygenic risk, our DNA Decoder recommends the type of physical activity (Low/Moderate/High Intensity) you should opt for along with the duration.